Bibliographic Detail  #394512    

Material Type Books
LC Call #RS403 P37 2013
AuthorPatrick, Graham L
TitleAn introduction to medicinal chemistry / Graham L. Patrick
EditionFifth edition
Published/CreatedOxford : Oxford University Press, c2013
Physical Descriptionxxiii, 789 pages : illustrations (some color) ; 25 cm
 Chemistry, Pharmaceutical
 Drug Design
 Pharmaceutical chemistry
ContentDrugs and drug targets: an overview -- Part A. Drug Targets: Protein structure and function -- Enzymes: structure and function -- Receptors: structure and function -- Receptors and signal transduction -- Nucleic acids: structure and function -- Part B. Pharmacodynamics and Pharmacokinetics: Enzymes as drug targets -- Receptorsas drug targets -- Nucleic acids as drug targets -- Miscellaneous drug targets -- Pharmacokinetics and relatedtopics -- Case study 1: Statins -- Part C. Drug Discovery,Design, and Development: Drug discovery: finding a lead --Drug design: optimizing target interactions -- Drug design: optimizing access to the target -- Getting the drug to market -- Case study 2: The design of angiotensin-converting enzyme (ACE) inhibitors -- Case study 3: Artemisinin and related antimalarial drugs -- Case study 4: The design of oxamniquine -- Part D. Tools of the Trade:Combinatorial and parallel synthesis -- Computers in medicinal chemistry -- Quantitative structure-activity relationships (QSAR) -- Case study 5: Design of a thymidylate synthase inhibitor -- Part E. Selected Topics in Medicinal Chemistry: Antibacterial agents -- Antiviral agents -- Anticancer agents -- Cholinergics, anticholinergics, and anticholinesterases -- Drugs acting on the adrenergic nervous system -- The opioid analgesics -- Anti-ulcer agents -- Case study 6: Steroidal anti-inflammatory agents -- Case study 7: Current research intoantidepressant agents
summaryThis volume provides an introduction to medicinal chemistry. It covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug
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30102000103448RS403 P37 2013BooksLady Atthakraweesunthorn Library 5th Floor   Available
LibraryOrdered DateCopiesStatus
Lady Atthakraweesunthorn Library25 Feb 20151Completely Received
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